The cost of carpal tunnel surgery depends on your location. The real cost of open carpal release surgery is not only about the money. In the United States you may expect a bill anywhere between $4,500 and $9000. This is only to cover the surgery and basic pre and post operation care. There’s still the cost of rehabilitation, loss of work, and many other factors to consider. In other words, surgery is more expensive than just the cost of the operation.